Efeitos do uso de Cannabis medicinal no tratamento da dor relacionada ao câncer: uma revisão sistemática

Ayra Lisiane Ferreira dos Santos; Eduardo Salomão Rodrigues Nascimento  dos Santos; Almir Vieira Dibai Filho; Cid André Fidelis de Paula Gomes; Caroline de Menezes Pinto; Cesário da Silva Souza

doi:10.5585/23.2024.26196

Authors

Ayra Lisiane Ferreira dos Santos Centro Universitário de Maceió https://orcid.org/0000-0002-0896-845X
Eduardo Salomão Rodrigues Nascimento dos Santos Centro Universitário de Maceió https://orcid.org/0000-0002-2428-1762
Almir Vieira Dibai Filho Federal University of Maranhão https://orcid.org/0000-0001-5403-8248
Cid André Fidelis de Paula Gomes july nine university https://orcid.org/0000-0001-6627-7537
Caroline de Menezes Pinto Centro Universitário de Maceió https://orcid.org/0000-0002-3218-1534
Cesário da Silva Souza Centro Universitário de Maceió https://orcid.org/0000-0002-1203-7754

DOI:

https://doi.org/10.5585/23.2024.26196

Keywords:

Analgesia, Cannabis, Cannabinoids, Cancer-related pain

Abstract

Introduction: Pain, considered a sensory experience that may be associated with injuries, can aggravate suffering in cancer patients.
Objective: To identify the effectiveness of products derived from the Cannabis genus in the treatment of cancer-related pain compared to other pain treatments and placebo in cancer patients.
Material and methods: Systematic review that followed the PRISMA checklist for its preparation. The research question was created using the PICO strategy, with the search terms being “Cancer pain”, “Cannabis” and “Cannabinoids”. Searches for studies were carried out in the PubMed, Embase and CENTRAL databases.
Results: The predominant interventions of the selected studies were the use of extracts of Cannabidiol (CBD), Tetrahydrocannabinol (THC) and CBD and THC compunds (Nabiximols); the main outcomes analyzed were pain relief and cancer-related symptoms.
Conclusion: The use of Cannabis derivatives to treat pain did not demonstrate superiority over conventional treatments or placebo.

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Author Biographies

Ayra Lisiane Ferreira dos Santos, Centro Universitário de Maceió

Master's student of the Postgraduate Program in Society, Technologies and Public Policies (SOTEPP) at Centro Universitário de Maceió, Maceió, AL, Brazil.

Eduardo Salomão Rodrigues Nascimento dos Santos, Centro Universitário de Maceió

Graduated in Physiotherapy – Centro Universitário de Maceió, Maceió, AL, Brazil.

Almir Vieira Dibai Filho, Federal University of Maranhão

Adjunct Professor of the Department of Physical Education of the Postgraduate Program in Physical Education at the Federal University of Maranhão (UFMA), São Luís, MA, Brazil.

Cid André Fidelis de Paula Gomes, july nine university

Professor of the Postgraduate Program in Rehabilitation Sciences at Universidade Nove de Julho (UNINOVE), São Paulo, SP, Brazil.

Caroline de Menezes Pinto, Centro Universitário de Maceió

Master's student of the Postgraduate Program in Society, Technologies and Public Policies (SOTEPP) at Centro Universitário de Maceió, Maceió, AL, Brazil.

Cesário da Silva Souza, Centro Universitário de Maceió

Professor do Programa de Pós-graduação em Sociedade, Tecnologias e Políticas Públicas (SOTEPP) do Centro Universitário de Maceió, Maceió, AL, Brasil.

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